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Medicinal use of Cannabis

Cardiovascular Effects of Cannabis

 

One of the most consistent effects of cannabis intoxication is an increased heart rate[i]. For this reason alone it would not be normally recommended for patients with cardiovascular problems. However, THC also acts as a smooth-muscle relaxant, relaxing the walls of the arteries, which can result in lower blood pressure and increased blood flow to the tissues[ii][iii]. The effect taken together is analogous to a car changing down a gear.

 

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Cannabis and Stress Anxiety

 

In recent IDMU surveys, relaxation and stress relief were overwhelmingly the most commonly perceived benefits of cannabis use.  However, the Department of Health identifies panic attacks and anxiety as effects of acute cannabis intoxication, particularly among naive users, in justifying the refusal of the UK Government to permit the prescribing of cannabis.

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Cannabinoids and the Gastrointestinal Tract

 

Although the use of cannabinoids as antiemetics (anti-nausea) is well-established, with Dronabinol available to stimulate appetite and counter effects of cancer chemotherapy, the effect of cannabinoids on disorders of the gut has only recently been extensively studied.

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Cannabinoids and Pain Relief

 

Pain relief (analgesia) or decreased pain sensitivity (antinociception)  are among the most commonly-cited therapeutic effects of smoking cannabis.  Although cannabis products have been used for thousands of years to treat pain and other conditions, it was not until the discovery of the ‘cannabis receptor’ in the late 1980s that modern medicine started to take cannabis seriously.

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Cannabinoids and Cancer


The use of cannabinoids in treating the side effects of cancer chemotherapy is more widely-studied than many other potential therapeutic applications, and a number of clinical studies have taken place investigating the use of THC and synthetic cannabinoids as anti-emetic agents.  Two preparations have been licensed for use in clinical treatment either in the UK or elsewhere, including dronabinol (synthetic THC) and Nabilone (a novel synthetic cannabinoid).

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